FUNCTIONAL IDENTIFICATION OF PGM1 IN THE REGULATING DEVELOPMENT AND DEPOSITING OF INOSINE MONOPHOSPHATE SPECIFIC FOR MYOBLASTS

Functional identification of PGM1 in the regulating development and depositing of inosine monophosphate specific for myoblasts

BackgroundInosine monophosphate (IMP) is naturally present in poultry muscle and plays a key role in improving meat flavour.However, IMP deposition is regulated by numerous genes and complex molecular networks.In order to excavate key candidate genes that may regulate IMP synthesis, we performed proteome and metabolome analyses on the leg muscle, c

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Expression alteration of microRNAs in Nucleus Accumbens is associated with chronic stress and antidepressant treatment in rats

Abstract Background Nucleus Accumbens (NAc) is a vital brain region for the process of reward and stress, whereas microRNA plays a crucial role in depression pathology.However, the abnormality of NAc miRNA expression during the stress-induced depression and antidepressant treatment, as well as its biological significance, are still unknown.Methods

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